Conceiving Via IVF Puts Mothers at Higher Risk of Digestive Diseases

Owing to the advent of modern technology in all fields of life, everything seems very easy and convenient. This has even helped having babies very easily for those who unfortunately has reproductive complications.

Nonetheless, now a new study by Turkish scientists has shown that women who get impregnated via in-vitro fertilization (IVF) are at elevated risk of suffering from prolonged symbols of gastro-esophageal reflux disease (GORD).


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The research team analyzed the results of two categories of women and compared them. The comparison was based to check the disparities between women who became a mother in no less than one year before via IVF and naturally. It was discovered that mothers of IVF babies are three-times more probable to be detected with GORD than those who became mothers through natural processes.

In the first category of women that comprised of 156 women who were experiencing motherhood for the first time, 54 gave birth to twins and 102 to single babies via IVF in no less than one year before. The researchers interviewed them face-to-face and asked them questions based on an authorized reflux questionnaire to assemble records on their pregnancies as well as to observe any symbols of GORD from occurrences of heartburn or regurgitation or both at least one time in seven days. The outcomes were then compared to the second controlled category of women who had the same age as that of the women in the first category and also had babies in no less than a year before, but naturally. The women who became mothers through natural processes also had to go through the same questionnaire.

The findings indicated that women who became mothers via IVF had 13.5 percent more chance of developing GORD as compared to just 4.5 percent in women who became mothers naturally. Additionally, albeit not statistically evident IVF mothers who had twins stood a higher chance of developing GORD at 14.8 percent than those who had single babies with 12.7 percent.

The researchers are still unclear about the mechanism behind IVF mothers becoming more susceptible to GORD. Nonetheless, they put forward a number of prospects even medications at the time IVF like high-dose of estrogen and progesterone, which calms the LOS, psychological pressures related to fertility matters like depression and worry, and the probability that the lying down might consume a lot of time for the women who undergo IVF treatment due to the fear of miscarriage.

Oliver Pech who is associated with St. John of God Hospital in Germany and the Associate Editor of the journal where the study was published termed the discoveries to be “very interesting” and that “UEG” (the name of the journal) would accept any  supplementary research in this field to establish whether these outcomes “cane be replicated in long-term, prospective studies.”

He emphasized that if evidence could be found then inspection needs to be conducted in order to try and prevent the prevalence of GORD “in all pregnant women, but particularly in those who receive IVF treatment.”

GORD is an ordinary state where the acid from the stomach ascents into the food pipe (esophagus) and triggers heartburn, regurgitation and pain while swallowing. Pregnancy is familiar as a risk-factor for fostering GORD as it affects nearly half of the pregnant women.

The research has been published in the “UEG Journal”.

According to American Society for Reproductive Medicine, IVF pregnancies have many other mild side effects. These include slight injuries and inflammation at the area where the injection was used, temporary allergic responses like reddening of skin and/or itching at the injection area, breast tenderness and elevated discharge from vagina and ovarian hyperstimulation syndrome (OHSS) – a mild condition of ovarian discomfort that in acute situation s can lead to huge amounts of fluid covering up the lungs and belly.

According to a report by Healthline, 7 million persons in U.S suffer from GORD. Of these, 60 percent of the adults is expected to suffer from some kind of GORD within a 12 month span while 20 to 30 percent will show weekly symptoms of the disease’s prevalence.

The same report also said that in 2004, nearly 20 percent of the American population reported of reflux complications with all of then occurring in no less than a week.

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